Liquid methionine analogue: a cost effective source of methionine with extra advantages

Wednesday, December 17, 2014

 

Liquid methionine analogue: a cost effective source of methionine with extra advantages

 

Javed Hayat and Kevin Liu, Adisseo Asia Pacific Pte Ltd

 

 

DL-hydroxy methionine, also known as liquid methionine analogue or (2-hydroxy-4-(methylthio) butanoic acid (HMTBA), delivers poultry industry the added value of not only a highly-effective methionine source, but also an efficient feed additive of proven acidifier properties. It is a fully efficient precursor of L-Met and other sulphur metabolites through sulphur amino acid pathways in the chicken (Dibner et al., 1988; Martin-Venegas et al., 2006 and 2013). An earlier absorptive ability of DL-hydroxy methionine compared to DLM was reported in broilers (Richard et al., 2005). Also the oligomers of DL-hydroxy methionine that were thought as limiting for absorption are not likely to be limiting point for intestinal absorption since they are hydrolysed at mucosal level (Martin-Venegas et al., 2006). DL-hydroxy methionine has a pKa of 3.86 (Dibner and Buttin, 2002) suggesting it contains strong organic acid capabilities. Moreover, Swennen et al. (2011) and Willemsen et al. (2010) suggested that DL-hydroxy methionine appeared to be more effective in sustaining antioxidant status of the cell mainly by maintaining higher reduced glutathione (GSH)/oxidized glutathione (GSSG) ratio.

 

 

For more of the article, please click here.


Article made possible through the contribution of Javed Hayat, Kevin Liu, and Adisseo Asia Pacific Pte Ltd

Video >
Technical Paper >
Subscribe Technical Forum eNewsletter
Please input your name.
Please input your company name.
Please input a valid email address.
Please input your job title.
Please select your business category.
By clicking Submit, I am agreeing to receive eFeedLink eNewsletter and understand that the information I've provided here will be saved by eFeedLink. eFeedLink guarantees that your details will not be shared with any third parties.