August 7, 2013


Coccidia challenge reveals combined effects of Diamond V Original XPC, Salinomycin


During a coccidia challenge, research was conducted investigating the individual and combined effects of feeding Diamond V Original XPC (a Saccharomyces cerevisiae fermentation product) and Salinomycin (an anticoccidial).


Three hundred twenty Cobb chicks were divided into five treatments at one day of age, with eight replicate pens/treatment and eight birds/pen. The treatments included: 1) non-treated, non-infected (NC), 2) non-treated, infected (PC), 3) Salinomycin treated, infected (SAL), 4) Original XPC treated, infected (XPC), and 5) Salinomycin plus XPC treated, infected (SAL-XPC). Additives were fed from one to 27 days, with dietary inclusion of Salinomycin at 66 gram/tonne and XPC at 1.25 kilogrammes/tonne.


At 21 days, birds were weighed and infected birds inoculated with a mixed Eimeria culture containing E. acervulina (EA), E. maxima (EM), and E. tenella (ET). Birds were weighed and lesion scored in the upper, middle, and cecal regions of the intestine six days post inoculation. Body weight gain (BWG) and feed conversion (FCR) were significantly (P < 0.05) improved in all treated, infected groups compared to PC during the coccidia challenge. Of the infected treatment groups, SAL-XPC had the highest BWG and lowest FCR, followed by SAL, and then XPC. A similar response was observed for lesion scoring in which all treated, infected groups had significantly (P < 0.05) lower EA, EM, and ET lesion scores compared to PC. No difference (P > 0.05) in EM lesion score was observed between the three treated, infected groups. Birds receiving SAL or SAL-XPC had significantly (P < 0.05) lower EA and ET lesion scores than XPC.


Overall, Salinomycin or Original XPC reduced coccidia lesions and the negative performance effects of the Eimeria challenge. The combination of both treatments resulted in the best improvement in performance during the challenge.