Lipopolysaccharide induces acute bursal atrophy in broiler chicks by activating TLR4-MAPK-NF-kB/AP-1 signaling

Tuesday, May 4, 2021
Lipopolysaccharide induces acute bursal atrophy in broiler chicks by activating TLR4-MAPK-NF-kB/AP-1 signaling
We investigated the mechanisms that induce atrophy of the chicken bursa of Fabricius (BF) upon lipopolysaccharide (LPS) treatment in young chicks. LPS treatment resulted in ~36% decrease in bursal weight within 36 h (P < 0.01). Histological analysis showed infiltration of eosinophilic heterophils and nucleated oval sha ...
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