December 7, 2011


Adisseo establishes Rovabio analytical laboratory in Singapore


Press Release 



Adisseo and Crown Pacific Biotechnology (CPB) in Singapore have established a joint laboratory to analyse Rovabio products and retention rates in feeds.


As the use of feed enzyme increases steadily across the region, enzyme assay, however, remains a great challenge to the industry. Unlike other feed additives or medicines, enzymes are of a variety of different live protein molecules with structures not fully illustrated.


The activity of a given single enzyme changes depending on substrate, reaction time, pH and temperature in its reaction medium. Feed enzyme products are usually mixture of a number of different enzyme activities, or similar activities but from different molecules. Its level of complicity results in no international standard or protocol to analyse feed enzymes by far. Notwithstanding, each enzyme producer uses its own protocol to define its products. As such, it makes no sense to compare enzyme activity among different suppliers.


Adisseo and Crown Pacific Biotechnology (CPB) in Singapore have made a significant move by setting up a joint laboratory to analyze Rovabio products and

retention rates in feeds, using a method developed by Carat Lab in France as the official method for Rovabio.


Instead of measuring activity of single enzyme against its specific substrate, this method employs a specific yet costly viscometer (AMVn) to measure viscosity reduction of given substrates, either feed ingredients or complete feeds. The results reflect collective responses of numerous enzymes, either naturally occurred or premixed as a cocktail. A parallel test between CPB Lab and Carat Lab in France, on 26 feed samples, shows 6.0% relative difference that confirms reliability of the new lab facility.


The method can be used to determine both enzyme products and retention rates after spray or pelleting. The lab is already in commercial services.

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