July 14, 2016

Evogene to present at Crops and Chemicals 2016 conference




Evogene Ltd., a leading biotechnology company for the improvement of crop productivity, has announced that its chief scientific officer, Dr. Eyal Emmanuel, will present initial results from the company's Insect Control Novel Toxin Discovery Program at the Crops and Chemicals Conference on July 19-21.


The event takes place in Raleigh, North Carolina, US.


During his presentation, Dr. Emmanuel will describe Evogene's unique approach for the discovery of microbial genes demonstrating insecticidal activity with  novel  'mode of action' and  will present preliminary results for certain selected genes.  The genes for which preliminary results will be provided include genes discovered from cultured bacteria as part of Evogene's programme with Marrone Bio Innovations Inc., as well as genes discovered from its proprietary, experiments incorporating metagenomics data. The candidate genes from both sources were discovered using the company's in silico algorithmic approach. Validation of the insecticidal activity for such genes included diet-based assays against several key target insects, demonstrating strong support for the unique methodologies utilised in Evogene's Insect Control Program.


Evogene's in silico approach for novel toxin discovery leverages two key proprietary technologies - comprehensive integrated databases, and a dedicated computational analysis platform (BiomeMinerTM). The integrated databases are enriched with microbial genes consisting of insecticidal activity from both cultured and uncultured bacteria (metagenomics), sourced from proprietary and public experiments. The BiomeMinerTM computational platform utilises advanced algorithms and machine learning technologies, and has been designed to sift through many millions of genes and pinpoint the most promising candidates to yield potential novel insecticidal modes of action.

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