Abrupt suspension of probiotics administration may increase host pathogen susceptibility by inducing gut dysbiosis

 

Zhi Liu, Wenshu Liu, Chao Ran, Jun Hu and Zhigang Zhou, Ministry of Agriculture, Feed Research Institute, Chinese Academy of Agricultural Sciences

            
           

In this study, we investigated the risk associated with suspension of probiotics administration in tilapia. Tilapias were fed for 14 days using a probiotics-supplemented diet, followed by a three-day suspension of probiotics treatment and a subsequent challenge by Aeromonas hydrophila. Unexpectedly, the suspension of a probiotic strain Lactobacillus plantarum JCM1149 significantly triggered susceptibility of the host to A. hydrophila.

  

  

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Article made possible through the contribution of Zhi Liu, Wenshu Liu, Chao Ran, Jun Hu and Zhigang Zhou, Ministry of Agriculture, Feed Research Institute, Chinese Academy of Agricultural Sciences

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