April 30, 2021


India's ICAR-CIBA develops nation's first vaccine for viral nervous necrosis of finfish


India's ICAR-Central Institute of Brackishwater Aquaculture (CIBA) of the Indian Council of Agricultural Research (Ministry of Agriculture and Farmers Welfare) announced that it has developed an indigenous vaccine for viral nervous necrosis (VNN) affecting several species of fish.

Dr. J.K. Jena, Deputy Director General (Fisheries), ICAR released the recombinant VNN vaccine, CIBA-Nodavac-R, in the presence of Dr. S. K. Chaudhari, Deputy Director General (NRM), ICAR and Dr. V. K. Singh, Director, ICAR-CRIDA in a virtual event held on April 27, 2021.

Dr. K.K.Vijayan, Director, ICAR-CIBA said that the vaccine will help to prevent VNN in fish hatcheries and bring down the incidence of VNN in grow-out farms.

VNN is a serious viral disease affecting many marine, brackishwater and freshwater fish causing up to 100% mortality in larval and early juvenile stages. The disease is caused by nervous necrosis virus (NNV). Red-spotted grouper nervous necrosis virus (RGNNV) is the only genotype prevalent in India and most other tropical countries. The disease is transmitted both vertically and horizontally. Infected adults remain as carriers and transmit the virus to offspring through eggs. The practical way to control the disease and prevent vertical transmission is to vaccinate fingerlings and adult fish.

CIBA-Nodavac-R is an injectable recombinant VNN vaccine which prevent VNN caused by RGNNV in fingerlings and prevent vertical transmission in brooders. The vaccine is said to be safe and efficacious, and can be used in all species susceptible to VNN such as milkfish, grey mullet, mangrove red snapper etc.

An oral vaccine for delivery through feed and an immersion vaccine are also under development.