By enforcing piglet health with an exogenous defence shield called Vitazero®, Nuscience provides a total solution for replacing zinc oxide at therapeutic dosages.

For decades, high dosages of zinc oxide (ZnO) have been used in piglet nutrition to prevent weaning diarrhea. However, current reports highlighted its negative effects on animal performance and the environment. The European Union decided to ban the use of ZnO by 2022 because of:

Increased antimicrobial resistance

Recent literature has shown that ZnO in feed and in the manure has a consistent function in the maintenance and proliferation of antibiotic-resistant genes (Cavaco et al., 2011).

Changed composition of intestinal microbiota in piglets

Dietary ZnO modulates the microflora of piglet by increasing the pathogenic Enterobacteriaceae group and decreasing the lactic acidproducing population. This is the most important reason why diarrhea is often seen as soon as ZnO is removed from the diet.

Accumulation in important vital organs
An imbalance of Zn homeostasis in the piglet's body results in an accumulation of Zn ions in organs such as the kidney, liver, and pancreas, leading to stress responses impairing its metabolism.

Environmental issues

Through the manure, large amounts of Zn ions are spreaded in the soil and can reach the water, causing changes in the composition of these natural sources used by humans for cultivation of food and daily routine.

Total approach

Only a multifactorial approach will succeed in tackling these challenges. In order to reduce antibiotics and replace ZnO in swine production, Nuscience offers a complete 'Zero-approach' including managerial support, nutritional expertise/optimisation and the feed additive Vitazero®.

Vitazero® provides the piglet with an exogeneous defense shield. A synergistic mixture of short and medium chain fatty acids kills pathogenic bacteria entering the stomach and regulates the intestinal flora by increasing the Lactobacilli population. Purified medium chain fatty acids not only have a high antimicrobial activity which increases the villus/crypt ratio; they also improve overall immunity. To prevent metabolic stress, a combination of natural antioxidants will lower the intestinal permeability and maintain the gut barrier. Finally, a uniquely upgraded fiber concept agglutinates pathogens in the intestine, thus creating a washout effect and blocking endotoxins from binding on intestinal receptors.

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