January 9, 2017

Hypor collaborates to identify genetic basis of disease resilient pigs




New research that investigates the genetic ability for pigs to respond to disease challenges in a natural environment is underway thanks to the collaboration of Hypor, PigGen Canada, and a team of researchers from the Universities of Alberta, Guelph, Saskatchewan, Iowa State and the Centre de Dévelopement du Porc du Québec (CDPQ).


"This is a unique approach in that it exposes pigs to multiple pathogens simultaneously," Hypor senior geneticist, Dr. Patrick Charagu, said. He explains that this research model is more informative than research that tests the genetic response to only one or two pathogens.


"Pigs may respond differently to each pathogen," Dr. Charagu added. "We want to see how they respond to exposure to a variety of types of diseases." Unlike other research programmes that challenge pigs with specific diseases via inoculation, the current research project exposes pigs to several pathogens in a natural environment, such as through pig-to-pig contact, the manure, general airborne exposure.


The goal for the three-year programme is to try to understand if there is underlying genetic explanation to how pigs respond to disease challenges. Approximately 3,500 Large White by Landrace cross (F1) barrows are health challenged and followed from wean to finish. Information and data, such as morbidity, mortality, growth and feed conversion, are collected from each of the pigs. Upon slaughter, carcass data is also recorded.


Each of the seven genetic companies that are members of PigGen Canada are supplying their pigs for the collaborative research project. Right at the beginning, prior to entering the research facility, pigs are tested for their innate ability to respond to a pathogen challenge (immune response). This information is then later compared to each pig's reaction to actual disease exposure once it enters the research facility.


The idea is that the research will help to identify, and if possible quantify, a pig's ability to withstand a disease challenge - a pig's ability to maintain a high level of performance under disease exposure. This is referred to as disease resilience or tolerance. "Ideally, this will help us to breed pigs that will be able to keep on performing optimally (e.g feed conversion and reproduction) even if they are on a disease-challenged farm," Dr. Charagu explained. "This would lower health costs and improve performance, and hence profitability, for the pork producer."


At the end of the day, pork producers want pigs on their farm that are going to make them a profit, Hypor said. The company's aim is to breed pigs that are profitable for the pork producer. This research fits right in place with Hypor's goal as a genetics company. Hypor's ambition is to breed animals that are good at withstanding all challenges while performing at a high level, the company stated.


- Hypor

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