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MLBA11: October / November 2009
 
Egg yolk IgY antibodies against avian coccidiosis infections­
 
By S.H. Lee, H.S. Lillehoj, D.W. Park, S.I. Jang, A. Morales, D. Garcı´a, E. Lucio, R. Larios, G. Victoria, D. Marrufo, Erik P. Lillehoj
 
 
Avian coccidiosis is an intesti­nal disease caused by several distinct species of Eimeria protozoa and is the most economi­cally significant parasitic infection of the poultry industry worldwide.
 
Due to increasing concerns with prophylactic drug use and high costs of vaccines, alternative control meth­ods need to be developed. Therefore, much recent interest has been devoted towards the development of drug-independent control strategies against coccidiosis.
 
An alternative control strategy po­tentially applicable to intestinal dis­eases such as avian coccidiosis, may involve a passive immunisation strat­egy using hyperimmune, pathogen-specific secretory IgY antibodies. For example, egg yolk IgY antibodies of­fer a practicable alternative to mam­malian serum antibodies because of their feasibility for large-scale com­mercial production and the relative non-invasive methods used for their preparation.
 
 
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